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Cells

Overview of Cells

These adipose-derived stem cells were developed through joint research between practicing clinicians and an academic research institution.

Physicians and medical institutions are required to establish and manage cultural processes and quality standards under the Act on the Safety of Regenerative Medicine. However, the law allows the outsourcing of cell culture to authorized companies, recognizing the potential difficulty for physicians or institutions to manage these processes directly.
TOPs cells are adipose-derived stem cells optimized for therapeutic use and have been developed with patient well-being as the highest priority.
They were cultured using a fat harvesting and cell culture method established through joint research with an academic research institution, under the guidance of a plastic surgeon with deep expertise in both clinical treatment and cell processing.
The adipose-derived stem cells cultured using this technique are named ‘TOPs Cells,' taking the initials from Tokyo (T), Orthopaedics (O), and Plastic Surgery (P). This approach enables the delivery of high-quality cells with minimal invasiveness.（Key Features of TOPs Cells）

Have you ever thought about something like this?

  • It is essential to respond appropriately to regulatory requirements...
  • We want to use safe and reliable Specific Processed Cells...
  • We aim to use Specific Processed Cells that were expected to offer greater therapeutic efficacy..
  • We aim to reduce both the physical and financial burden on patients...

“Uncompromising in Stem Cell Cultivation.”​
“The cells are the patient’s own.”

We believe that each cell is like a patient under our care.
Our cell culture specialists approach their work with awareness that they are also healthcare professionals.
The cells entrusted to us were observed carefully each day and handled with utmost care, individually, with respect and responsibility.

Founder: Shinsaku Tsuji, M.D.​

An academic research institution × Medical Institutions × CPC

We are committed to improve the quality of cells further and establish robust scientific and clinical evidence through the fusion of advanced technologies and insights from clinical practice.

  • Bench (Research):
    Building the Foundations of Regenerative Medicine Through Cell Culture Innovation     Through collaborative research with various companies, we are developing specialized culture media and scaffold materials and continuously working to optimize cell culture technologies to reduce the burden on patients. Our ongoing efforts include elucidating the mechanisms underlying cell behavior, establishing new large-scale culture processes, developing quality assessment methods at the molecular and genetic levels, and exploring potential applications of culture supernatants.
  • Bedside (Clinical):
    Advancing Adipose-Derived Stem Cell Therapy through Clinical Outcome Analysis​     Our partner medical institutions are analyzing clinical outcomes in conditions such as knee osteoarthritis and frailty through multicenter collaborative research. These analyses evaluate the efficacy and safety of the treatments and, examine patient backgrounds and patterns of functional recovery following therapy. Furthermore, the aim is to deepen our understanding of appropriate treatment indications and long-term outcomes by integrating data from the participating facilities.
  • Business (Business):
    Promoting the Widespread Use of TOPs Cells     We aim to deliver TOPs cells to a greater number of patients by supporting the implementation of regenerative medicine in medical institutions and providing contract-based cell culture services. In addition, we are building a robust database on the efficacy and safety of treatments, creating an environment in which medical institutions can adopt these therapies with confidence. We also engage in outreach to healthcare professionals through academic activities such as conference presentations, peer-reviewed publications, and seminars, contributing to the advancement of regenerative medicine.