Cells
TOPs Cells
TOPs cells are adipose-derived stem cells developed using fat extraction and cultivation methods and cultivated through joint research between CPC Co., Ltd. and the Department of Orthopedic Surgery at the University of Tokyo. With the mission of delivering high-quality, low-burden, and reliable stem cell treatments to several patients, we have worked with many frontline physicians have worked to improve TOPs cells. We will continue to contribute to advancements in regenerative medicine and cell therapy.
Commitment to Cells
Minimally Invasive
Development of a specialized biopsy needle
Using biopsy needles for extraction and minimally invasive fat collection has become possible. As the wound is small, there is no need for sutures or stitch removal, and scarring is minimal.
Quality
Minimizing damage to cells
normally, the process of isolating stem cells from adipose tissue damages the tissue and can harm cells. However, through joint research by CPC Co., Ltd., University of Tokyo’s Department of Orthopedic Surgery, and partner companies, we developed a special nonwoven fabric that can be used to isolate stem cells without damaging the tissue. This process minimizes cell damage and enables stem cell collection from small amounts of adipose tissue. (Chijimatsu et al. Regen Ther. 2022)
Development of a unique culture medium
CPC Co., Ltd., in collaboration with the University of Tokyo’s Department of Orthopedic Surgery and partner companies, has led to the development of a proprietary culture medium that is produced domestically, ensuring the stable production of high-quality stem cells.
Delivery of unfrozen stem cells
Stem cells isolated from the adipose tissue are expanded to an adequate number and cryopreserved. On the day of administration, the cells are thawed and undergo a final culture. The stem cells obtained from this final culture are not frozen but are transported under proper temperature control to ensure that freshly cultured stem cells are delivered to the patient.
Joint Research
with the University of
Tokyo’s Department
of Orthopedic Surgery
To make stem cell therapy even more effective and accessible to more patients, we will continue our research and contribute to the advancement of regenerative medicine and cell therapy.
